| Population Genetics |
| 1. |
Explain the statement “It is the population, not the individual, that evolves.” |
| 2. |
Explain how Mendel’s particulate hypothesis of inheritance provided much-needed support for Darwin’s theory of evolution by natural selection. |
| 3. |
Distinguish between discrete and quantitative traits. Explain how Mendel’s laws of inheritance apply to quantitative traits. |
| 4. |
Explain what is meant by “the modern synthesis.” |
| 5. |
Define the terms population, species, and gene pool. |
| 6. |
Explain why meiosis and random fertilization alone will not alter the frequency of alleles or genotypes in a population. |
| 7. |
List the five conditions that must be met for a population to remain in Hardy-Weinberg equilibrium. |
| 8. |
Write the Hardy-Weinberg equation. Use the equation to calculate allele frequencies when the frequency of homozygous recessive individuals in a population is 25%. |
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Mutation and Sexual Recombination |
| 9. |
Explain why the majority of point mutations are harmless. |
| 10. |
Explain why mutation has little quantitative effect on allele frequencies in a large population. |
| 11. |
Describe the significance of transposons in the generation of genetic variability. |
| 12. |
Explain how sexual recombination generates genetic variability. |
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Natural Selection, Genetic Drift, and Gene Flow |
| 13. |
Explain the following statement: “Only natural selection leads to the adaptation of organisms to their environment.” |
| 14. |
Explain the role of population size in genetic drift. |
| 15. |
Distinguish between the bottleneck effect and the founder effect. |
| 16. |
Describe how gene flow can act to reduce genetic differences between adjacent populations. |
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Genetic Variation, the Substrate for Natural Selection |
| 17. |
Explain how quantitative and discrete characters contribute to variation within a population. |
| 18. |
Distinguish between average heterozygosity and nucleotide variability. Explain why average heterozygosity tends to be greater than nucleotide variability. |
| 19. |
Define a cline. |
| 20. |
Define relative fitness.
a. Explain why relative fitness is zero for a healthy, long-lived, sterile organism.
b. Explain why relative fitness could be high for a short-lived organism. |
| 21. |
Distinguish among directional, disruptive, and stabilizing selection. Give an example of each mode of selection. |
| 22. |
Explain how diploidy can protect a rare recessive allele from elimination by natural selection. |
| 23. |
Describe how heterozygote advantage and frequency-dependent selection promote balanced polymorphism. |
| 24. |
Define neutral variations. Explain why natural selection does not act on these alleles. |
| 25. |
Distinguish between intrasexual selection and intersexual selection. |
| 26. |
Explain how female preferences for showy male traits may benefit the female. |
| 27. |
Describe the disadvantages of sexual reproduction. |
| 28. |
Explain how the genetic variation promoted by sex may be advantageous to individuals on a generational time scale. |
| 29. |
List four reasons why natural selection cannot produce perfect organisms. |