Category: 1st Semester

Chapter 1 Worksheet BI

 

Biology – Science of Life

 

Section 1-1            Themes of Biology 

1. How many species of organisms are estimated to inhabit the Earth? 

2. About how many species have actually been identified? 

3. When did the first life forms probably arise on Earth? 

4. What was the first organism like? 

5.  What is an organism? 

6. Most unicellular organisms can only be seen with a __________________________.

7. Where did these first cells live? 

8. Over time, organisms _____________ and new kinds of _______________ arose from ___________ of organisms and came to inhabit every _______________ of the Earth. 

9. Define biology. 

10. Name several things that the study of biology would include. 

11. The study of biology is unified by ___________________________. 

12. Name 6 unifying themes of biology. 

13. What is a cell? Where are they found? 

14. What is the difference between a unicellular & a multicellular organism? 

15. Cells are ___________________ but highly _______________________.

16. Are all cells alike? Explain. 

17. All cells are surrounded by a ____________ & contain _____________  instructions. 

18. Genetic instructions are used by cells to make new __________ and new cell ________________. 

19. How do new cells produced by unicellular organisms compare to the parent unicellular organism? 

20. How do mature multicellular organisms begin their life? 

21. If multicellular organisms begin their life as one cell, how do they have so many cells? Explain. 

22. Give an example of an organism maintaining a stable internal environment. 

23. Define homeostasis and tell whether it occurs in unicellular&/or multicellular organisms. 

24. Genetic information is passed to offspring during _______________________.

25. What molecule contains the cell’s hereditary information?

26.  How does DNA exist in multicellular organisms? In unicellular organisms? 

27. What is a gene?

28. In multicellular organisms, each body cell has an _____________ copy of its DNA.

29. Does each cell in a multicellular organism use all the genes on its DNA? Explain. 

30. Explain sexual reproduction. 

31. When a sperm joins with an egg to make a fertilized cell, what happens next to this cell? 

32. New organisms from sexual reproduction have _______________ material from both parents.

33. Explain asexual reproduction. 

34. Name a unicellular organism that reproduces by asexual reproduction.

35. New cells or organisms from asexual reproduction have ____________ genetic information. 

36. What is evolution? 

37. Do individuals or populations evolve? 

38. What is the driving force for evolution? 

39. Explain natural selection and give an example. 

40. Competition for what types of resources drives natural selection? 

41. Why is it so important to a species for members to survive? 

42. Organisms that survive and reproduce are ones with ________________ traits.

43. Define ecology. 

44. What are ecosystems and give an example? 

45. Name 3 things organisms must get from the environment to survive. 

46. What has been the effect of man’s activities on many ecosystems? 

47. Living things are _______________ and need a constant supply of _________________.

48. What process supplies energy for organisms on Earth? 

49. Define autotroph. 

50. Autotrophs trap _________ and use this energy to combine __________ and  _________ into__________ and starches. 

51. Define heterotrophs. 

52. Give an example of an autotroph.

53. Give several examples of heterotrophs. 

54. How do heterotrophs get their food? 

Section 1-2            World of Biology 

55. List 6 characteristics shared by all living things. 

56. All living things composed of  _________________.

57. Cells may be specialized in _________________ organisms. What does this mean?

58. What is always true about cell size?

59. Living things are organized at what 2 levels?

60. How are cells organized in multicellular organisms?

61. Define metabolism. 

62. The energy from metabolism is used for ___________, ___________, and _______________ of organisms. 

63. What is homeostasis and give an example? 

64. Is growth a characteristic of living and nonliving things? Explain.

65. What 2 things must occur for living things to grow?

 

 

66. Define cell division.

 

 

 

67. Define development.

 

 

 

68. Explain why development is necessary for multicellular organisms?

 

 

 

69. Is reproduction essential to the survival of a species? Explain.

 

 

 

70. Sexual reproduction produces offspring ______________________ to the parents.

 

71. Have all organisms been identified? Explain.

 

 

Section 1-3            Scientific Method

 

72. Scientists solve problems using the ___________________________.

 

73. The first step of the scientific method is when scientists make ___________________ of the natural world.

74. Define data.

 

 

 

75. What does a scientist usually employ in making their observations?

 

 

76. What is quantitative data?

 

77. What is sampling & why is it used by scientists?

 

 

 

78. What 2 things must be true for samples to be useful?

 

 

79. To be useful, data must be _____________________ into ____________________,

 

       ______________________, and _____________________, or maps.

 

80. Once an observation is made, the second thing a scientist must do is to develop a(n) ___________________________.

 

81. Define hypothesis.

 

 

 

82. All hypotheses must be __________________ to give supporting evidence.

 

83. What is a prediction & how are they usually written?

 

 

 

84. What is an experiment?

 

 

 

85. Name the 2 groups in a controlled experiment.

 

 

86. Both groups in an experiment are identical except for ___________ factor called the

 

       ___________________.

87. Name the 2 types of variables in a controlled experiment.

 

 

 

88. After data is collected and organized, it must be __________________ to tell if it is reliable.

 

89. If experimental data does not support the hypothesis, what should be done?

 

 

90. What is a scientific model?

 

 

91. What is an inference?

 

 

 

92. How is a theory formed?

 

 

93. Define theory.

 

 

94. What is the difference between a field biologist and a laboratory biologist? Do they both use the scientific method?

 

 

 

 

95. What do scientists do with the results of their scientific studies?

 

 

 

Section 1-4            Microscopes & Measurement

 

96. What is a microscope?

 

 

97. What is the difference between resolution & magnification?

 

 

 

 

98. When would a microscope be used?

 

 

99. Do all microscopes have the same magnification & resolution?

 

100.  Draw and label the parts of a light (LM) microscope.

 

 

 

 

 

 

 

 

 

101. Tell the function of each of these parts of an LM — stage, light source, objective lens, ocular lens, & nosepiece.

 

 

 

 

 

 

102. To view specimens with a light microscope, they must be placed on a _______________

 

         and be ________________ so light will pass through to the lenses & your eyes.

 

103. What is the power of magnification & explain how it is determined?

 

 

 

104. Light microscopes can only magnify up to ______________ before the image becomes blurry.

105. What type of scope is used to view viruses & cell parts?

 

106. What produces an image with the electron microscope?

 

 

107. Name the 2 main types of electron microscopes.

 

108. What is the highest magnification for the TEM? For the SEM?

 

 

109. Can electron microscopes be used to view living cells?

 

110. What type of scope gives a magnified view of an object’s surface?

 

111. What is the standard unit of measurement used by scientists?

 

112. Name the SI base units, what they measure, & give their abbreviations (table 1-1, page 23)

 

 

 

 

 

 

113. The SI system is based on units of __________ with designated _________________.

 

114. Give the SI prefix for these base units — 1000, .01, .001, .000001, .000000001, & .000000000001.

 

 

 

 

 

115. Give the SI unit for area, volume, and time.

 

 

Chapter 16 – Molecular Basis of Inheritance

 

Chapter 16   Molecular Basis of Inheritance
Objectives
DNA as the Genetic Material
1. Explain why researchers originally thought protein was the genetic material.
2. Summarize the experiments performed by the following scientists that provided evidence that DNA is the genetic material:
a. Frederick Griffith
b. Oswald Avery, Maclyn McCarty, and Colin MacLeod
c. Alfred Hershey and Martha Chase
d. Erwin Chargaff
3. Explain how Watson and Crick deduced the structure of DNA and describe the evidence they used. Explain the significance of the research of Rosalind Franklin.
4. Describe the structure of DNA. Explain the base-pairing rule and describe its significance.
DNA Replication and Repair
5. Describe the semiconservative model of replication and the significance of the experiments of Matthew Meselson and Franklin Stahl.
6. Describe the process of DNA replication, including the role of the origins of replication and replication forks.
7. Explain the role of DNA polymerases in replication.
8. Explain what energy source drives the polymerization of DNA.
9. Define antiparallel and explain why continuous synthesis of both DNA strands is not possible.
10. Distinguish between the leading strand and the lagging strand.
11. Explain how the lagging strand is synthesized even though DNA polymerase can add nucleotides only to the 39 end. Describe the significance of Okazaki fragments.
12. Explain the roles of DNA ligase, primer, primase, helicase, topoisomerase, and single-strand binding proteins.
13. Explain why an analogy can be made comparing DNA replication to a locomotive made of DNA polymerase moving along a railroad track of DNA.
14. Explain the roles of DNA polymerase, mismatch repair enzymes, and nuclease in DNA proofreading and repair.
15. Describe the structure and function of telomeres.
16. Explain the possible significance of telomerase in germ cells and cancerous cell.

 
BACK

Introduction Notes

Introduction

All Materials © Cmassengale

Study of Life  

  • First life forms arose on Earth more than 3.5 billion years ago  
  • Single-celled, microscopic organisms (living thing) appeared first & floated alone in seas  
  • Over 40 million species (types of organisms) exist with only about 2 million identified 
  • Many organisms are unidentified & new species are still discovered  
  • Biology is the study of all living things and how they interact with each other & their environment  
  • Over long periods of time, species changed or evolved so that new species arose from earlier organisms & came to inhabit almost every part of the earth (bacteria living in thermal vents, parasites living inside another organism, etc.)  
  • Organisms must adapt to their specific environment to survive & reproduce

 

Unifying Themes of Biology 

 The six unifying themes include:  

  1. Cell Structure & Function
  2. Stability & Homeostasis
  3. Reproduction & Inheritance
  4. Evolution
  5. Interdependence of Organisms
  6. Matter, Energy, & Organization

Cell Structure & Function  

  • Cell is the basic unit of structure & function  
  • All organisms are made of one or more cells; Unicellular (one celled) or Multicellular (Composed of more than one cell)  


UNICELLULAR AMOEBA

  • Cells are small but highly organized; they contain specialized structures that carry out the jobs of a cell called organelles  


CELLULAR ORGANELLES

  • There are many different kinds of cells, but all cells have similarities
  • All cells are surrounded by a cell membrane, contain cytoplasm, and have DNA (the genetic information for making new cells or cell structures)  
  • New cells made by unicellular organisms are identical (clones) to the parent cell that produced them – asexual reproduction  
  • Multicellular organisms begin life as one fertilized cell (sexual reproduction), but the cells multiplied and underwent differentiation (changed structure & function) to become many different kinds of cells  

Stability & Homeostasis  

  • All organisms maintain stable internal conditions such as body temperature & water content
  • Stable level of internal conditions called homeostasis  

Reproduction & Inheritance  

  • All organisms reproduce new organisms like themselves by transmitting hereditary material to their offspring  
  • DNA (Deoxyribonucleic acid) is a large molecule containing the hereditary material of the cell


DNA MODEL

  • In unicellular organisms like bacteria, DNA exists as a single loop or chromosome in the cytoplasm  


BACTERIA

  • In multicellular organisms, DNA is enclosed in a membrane known as the nucleus 
  • Genes are short segments of DNA the carry the instructions for a single trait of an organism  
  • DNA of a cell contains all of the genes (instructions) it will ever need  
  •  All body cells have a complete set of DNA (genome), but different types of cells use certain genes from the set; example: Muscle cells have the genes to make thyroxine, but they don’t use these genes  
  • In sexual reproduction, an egg (ovum) is fertilized by a sperm to form a zygote so the new organism is made of cells with hereditary information from both parents  
  • In asexual reproduction, cells copy their DNA & split so all new cells are identical  

Evolution  

  • Populations of organisms change over time or evolve (Theory of Evolution)  


DARWIN – THEORY OF EVOLUTION

  • Natural selection or “survival of the fittest” is the process that drives evolution  
  • Organisms with favorable traits are better able to survive & reproduce  
  • The survival of organisms with favorable traits causes a gradual change in populations of organisms over many generations  
  • Evolution by natural selection is driven by competition for resources such as food, habitat, mates  

Interdependence of Organisms  

  • Ecology is the study of the interaction of organisms with each other and their environment  
  • Sunlight is the ultimate energy for all organisms  
  • Energy from the sun is passed from one organism to another; producers (plants) to herbivore (plant eater) to carnivore (meat eater) to decomposers (break down dead organisms)  


ENERGY FLOW IN A FOOD CHAIN

  • Abiotic (nonliving factors) such as air, water, energy, soil, temperature, & minerals are also needed for survival  
  • Biotic factors include all living things on earth (plants, animals, fungi, microorganisms)  
  • Biosphere supports life & includes the biotic (all organisms) & the abiotic (all nonliving factors) on earth  
  • Organisms respond to their environment by:
    * Fleeing
    * Adapting
    * Dying
  • Most organisms can survive a temporary change, but permanent change can lead to extinction (dinosaurs)  
  • Thousands of species are listed endangered (population so small could become extinct)  
  • Human interference is the main cause for endangerment & extinction
    * Pollution of land, air, and water
    *Hunting for sport, food, and commercial products also threatens the survival of many organisms
    * Clear-cutting rain forests
    * Diverting rivers & lakes
    * Draining wetlands (everglades)
    *Global Warming  
  •   Endangered organisms can be protected & returned to larger population size (American Bison almost wiped out –60 million to 250 in 90 years- now several thousand herds)  


AMERICAN BISON

  • Species is a group of organisms so similar to one another that they can interbreed & produce fertile offspring  
  •  Extinction of any species upsets the balance of nature (Almost extinct Pacific Yew tree found to contain chemical used to treat cancer)  


PACIFIC YEW TREE

Matter, Energy, & Organization  

  • Organisms are highly organized, maintain internal order, & require a constant energy supply
  • Plants & unicellular organisms with chlorophyll capture sunlight through photosynthesis & store it in food to be used by other organisms  
  • Autotrophs or producers use sunlight, water, & carbon dioxide to make glucose (energy rich sugar) & oxygen – photosynthesis  

  • Heterotrophs (consumers) feed on producers or other consumers to get energy & release carbon dioxide  

   Biology affects life in many ways  

  • Biotechnology uses organisms to make products needed by people (human insulin made by bacteria)
  •   Fossils fuels (coal, oil, & natural gas) provide energy & materials such as nylon & polyester  


OIL DRILLING

  • Animal products such as wool, silk, and leather make clothing  
  •  Wood provides energy & shelter for us, but endangers other animals (spotted owl) when forests are cut  
  • New medicines, better water treatment & garbage disposal improves our health
BACK

Chapter 17 AP Objectives

 

Chapter 17    From Gene to Protein
Objectives
The Connection Between Genes and Proteins
1. Explain why dwarf peas have shorter stems than tall varieties.
2. Explain the reasoning that led Archibald Garrod to first suggest that genes dictate phenotypes through enzymes.
3. Describe Beadle and Tatum’s experiments with Neurospora and explain the contribution they made to our understanding of how genes control metabolism.
4. Distinguish between the “one geneÐone enzyme” hypothesis and the “one geneÐone polypeptide” hypothesis and explain why the original hypothesis was changed.
5. Explain how RNA differs from DNA.
6. Briefly explain how information flows from gene to protein.
7. Distinguish between transcription and translation.
8. Compare where transcription and translation occur in prokaryotes and in eukaryotes.
9. Define codon and explain the relationship between the linear sequence of codons on mRNA and the linear sequence of amino acids in a polypeptide.
10. Explain the early techniques used to identify what amino acids are specified by the triplets UUU, AAA, GGG, and CCC.
11. Explain why polypeptides begin with methionine when they are synthesized.
12. Explain what it means to say that the genetic code is redundant and unambiguous.
13. Explain the significance of the reading frame during translation.
14. Explain the evolutionary significance of a nearly universal genetic code.
The Synthesis and Processing of RNA
15. Explain how RNA polymerase recognizes where transcription should begin. Describe the promoter, the terminator, and the transcription unit.
16. Explain the general process of transcription, including the three major steps of initiation, elongation, and termination.
17. Explain how RNA is modified after transcription in eukaryotic cells.
18. Define and explain the role of ribozyme.
19. Describe the functional and evolutionary significance of introns.
The Synthesis of Protein
20. Describe the structure and functions of tRNA.
21. Explain the significance of wobble.
22. Explain how tRNA is joined to the appropriate amino acid.
23. Describe the structure and functions of ribosomes.
24. Describe the process of translation (including initiation, elongation, and termination) and explain which enzymes, protein factors, and energy sources are needed for each stage.
25. Describe the significance of polyribosomes.
26. Explain what determines the primary structure of a protein and describe how a polypeptide must be modified before it becomes fully functional.
27. Describe what determines whether a ribosome will be free in the cytosol or attached to the rough endoplasmic reticulum.
28. Describe two properties of RNA that allow it to perform so many different functions.
29. Compare protein synthesis in prokaryotes and in eukaryotes.
30. Define point mutations. Distinguish between base-pair substitutions and base-pair insertions. Give examples of each and note the significance of such changes.
31. Describe several examples of mutagens and explain how they cause mutations.
32. Describe the historical evolution of the concept of a gene.

 
BACK

Protein Synthesis Quiz

Name: 

DNA & Protein Synthesis

 

 

True/False
Indicate whether the sentence or statement is true or false.
1.
When a tRNA anticodon binds to an mRNA codon, the amino acid detaches from the tRNA molecule and attaches to the end of a growing protein chain.
2.
Only ribosomal RNA plays a role in translation.
3.
During DNA replication, the molecule unzips and the exposed DNA nucleotides pair with other
specific nucleotides present in the nucleus
4.
Humans pass exact copies of their DNA to their offspring.
5.
Watson and Crick proposed a model of DNA
6.
Amino acids are linked together by hydrogen bonds.
7.
During transcription, the information on a DNA molecule is “rewritten” into an mRNA molecule.
8.
All codons encode amino acids.
 

Multiple Choice
Identify the letter of the choice that best completes the statement or answers the question.
9.
Purines and pyrimidines are
a.
bases found in amino acids.
b.
able to replace phosphate groups from defective DNA.
c.
names of specific types of DNA molecules.
d.
bases found in nucleotides.
10.
Chargaff’s rules, or the base-pairing rules, state that in DNA
a.
the amount of adenine equals the amount of thymine.
b.
the amount of guanine equals the amount of cytosine.
c.
the amount of guanine equals the amount of thymine.
d.
Both a and b
11.
ATTG : TAAC ::
a.
AAAT : TTTG
c.
GTCC : CAGG
b.
TCGG : AGAT
d.
CGAA : TGCG
12.
Which of the following types of RNA carries instructions for making proteins?
a.
mRNA
c.
tRNA
b.
rRNA
d.
All of the above
13.
Which of the following is not found in DNA?
a.
adenine
c.
uracil
b.
cytosine
d.
None of the above
14.
Suppose that you are given a polypeptide sequence containing the following sequence of amino acids: tyrosine, proline, aspartic acid, isoleucine, and cysteine. Use the portion of the genetic code given in the table below to determine the DNA sequence that codes for this polypeptide sequence.
mRNA
Amino acid
UAU, UAC
tyrosine
CCU, CCC, CCA, CCG
proline
GAU, GAC
aspartic acis
AUU, AUC, AUA
isoleucine
UGU, UGC
cysteine
a.
AUGGGUCUAUAUACG
c.
GCAAACTCGCGCGTA
b.
ATGGGTCTATATACG
d.
ATAGGGCTTTAAACA
15.
In order for protein synthesis to occur, mRNA must migrate to the
a.
ribosomes.
c.
RNA polymerase.
b.
lac operon.
d.
heterochromatin.
16.
After the primary structure of a protein has been completed
a.
the codons and anticodons unite.
b.
an enzyme attaches adjacent amino acids to each other to form a chain.
c.
the protein folds into the secondary and tertiary structures.
d.
the tRNA molecules remain attached until the protein is secreted from the cell.
17.
Which of the following is  not  part of a molecule of DNA?
a.
deoxyribose
c.
phosphate
b.
nitrogenous base
d.
ribose
18.
During replication in a molecule of DNA, one separation likely to occur is between
a.
cytosine and guanine
c.
ribose and adenine
b.
phosphate and deoxyribose
d.
uracil and thymine
19.
A gene may be described as
a.
a sequence of amino acids.
b.
special proteins found in chromosomes.
c.
a sequence of nucleotides that controls the production of a certain protein.
d.
a sequence of nucleotides coding for the production of starches and sugars.
20.
The synthesis of a new double strand of DNA begins when the two strand of the original DNA helix
a.
‘unzip’.
c.
attract nitrogenous bases.
b.
act as a template.
d.
destroy a genetic code.
21.
Genes(DNA) affect cell structure and function by directing the synthesis of
a.
nucleic acids
c.
nucleotides
b.
hereditary traits
d.
proteins
22.
Protein molecules are made up of
a.
fats
c.
lipids
b.
nucleotides
d.
amino acids
23.
During, DNA replication, DNA
a.
converts to RNA
c.
joins mRNA
b.
joins tRNA
d.
strands separate
24.
Which is not true about proteins?
a.
They control biochemical pathways within the cell.
b.
They direct the synthesis of lipids.
c.
They are composed of sugars.
d.
They take responsibility for cell movement.
25.
Molecules of DNA are composed of long chains of
a.
amino acids.
c.
monosaccharides.
b.
fatty acids.
d.
nucleotides.
26.
Watson and Crick were the first scientists to state that DNA
a.
contains phosphate groups
c.
has four nitrogen bases
b.
undergoes transcription
d.
has a double helix shape
27.
The two chains of a DNA molecule are connected by
a.
nitrogen bonds
c.
bases
b.
relatively weak chemical bonds
d.
nucleotides
28.
All nucleotide molecules contain the same kind of
a.
ribose sugar
c.
pyrimidine
b.
purine
d.
phosphate group
29.
After DNA replication, the two DNA molecules that are made
a.
are complementary.
c.
must replicate again.
b.
are identical.
d.
cannot replicate again.
30.
Sixty-four codons for 20 amino acids requires that
a.
some amino acids lack codons
b.
some amino acids have more than one codon
c.
all amino acids have two codons
d.
none of the above
31.
Which of the following combines with amino acids
a.
DNA
c.
tRNA
b.
mRNA
d.
B and C
32.
rRNA has a function in
a.
synthesizing DNA.
c.
forming ribosomes.
b.
synthesizing mRNA.
d.
transferring amino acids to ribosomes.
33.
The DNA code consists of sequences of nucleotides arranged in groups of
a.
variable number
c.
threes
b.
twos
d.
fours
34.
Unlike mRNA, the DNA molecule is
a.
double-stranded
c.
like a ladder
b.
single-stranded
d.
both A and C
35.
The number of bases in a row in a gene that codes a protein composed of 200 amino acids is
a.
200
c.
600
b.
400
d.
800
36.
A DNA molecule unzips during
a.
replication
c.
translation
b.
transcription
d.
both A and B
37.
A DNA chain has the following sequence of bases, TAG.  The corresponding messenger RNA
chain should have the sequence
a.
ATC
c.
ATG
b.
UTC
d.
AUC
38.
Unlike DNA, RNA
a.
contains deoxyribose.
c.
contains thymine.
b.
is double stranded.
d.
contains uracil.
39.
Which molecule contains deoxyribose
a.
DNA
c.
tRNA
b.
mRNA
d.
both B and C
40.
Each combination of three nitrogenous bases on messenger RNA forms a (an)
a.
anticodon.
c.
enzyme.
b.
codon.
d.
nuclei acid.
41.
In RNA, uracil is complementary to:
a.
guanine
c.
thymine
b.
adenine
d.
cytosine
42.
Once a molecule of transfer RNA has released its amino acid, the tRNA
a.
becomes attached to messenger RNA.
b.
becomes attached to ribosomal RNA.
c.
is destroyed as an individual molecule.
d.
moves away to pick up another amino acid.
43.
If the sequence of bases in a segment of a DNA strand were cytosine, guanine, adenine, thymine, adenine, then the sequence in a complimentary strand of newly-made mRNA would be
a.
cytosine, uracil, adenine, guanine, uracil
c.
uracil, adenine, cytosine, uracil, guanine
b.
guanine, cytosine, uracil, adenine, uracil
d.
cytosine, guanine, uracil, uracil, adenine
44.
Which sugar is present in RNA
a.
glucose
c.
ribose
b.
sucrose
d.
deoxyribose
45.
RNA differs from DNA, in that RNA
a.
is single-stranded.
c.
contains the nitrogen base uracil.
b.
contains a different sugar molecule.
d.
All of the above are correct.

 
Check Your Work     Reset