| Unit 5 Molecular Genetics Study Guide |
ü Be able to describe & explain the experiments of the following scientists:
Frederick Griffith
Erwin Chargraff
Alfred Hershey
Martha Chase
Watson & Crick
Meselson & Stahl
Beadle & Tatum
“Dolly” experiment
ü Know how DNA replicates including steps & the enzymes involved, energy required, nucleotides, leading & lagging strands, proofreading
ü Be able to describe the ultrastructure of each component of the DNA & RNA molecules
ü Know the steps of transcription, enzymes involved, etc
ü Know the steps of translation, enzymes involved, etc.
ü Be able to describe the structure & function of free and bound ribosomes
ü Know the processing steps of newly made mRNA
ü Know the types of mutations and their effects
ü Know viral structure, reproduction, host recognition, viral genome, etc
ü Be able to describe the prokaryotic genome, mechanisms for genetic recombination, & defenses against phages
ü Differentiate between hetero- & euchromatin
ü Know the function and use of restriction enzymes
ü Be able to describe genomic differentiation
