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Introduction, Chemistry, & Nature of Science Test
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Cells and Their Functions
Use this question bank to review cell structure, organelles, membranes, transport, and signaling. It retains the original 108 question numbers so teachers can assign selected items.
How to use: Choose one answer, A–E, and record it on paper or in your own answer document. Explain your reasoning for selected questions. This version does not submit, save, or automatically grade responses.
Before starting, review cell parts and their functions and the membrane transport study guide. Teachers should choose items that match their course and review the figures before assigning them.
Learning goals: relate cellular structures to their functions; interpret diagrams and scale; distinguish passive, active, and vesicular transport; and explain how cells communicate.
Cell theory, size, and microscopy
Question 1
The smallest unit that can carry out all activities we associate with life is:
- atom.
- organelle.
- cell.
- tissue.
- organ.
Question 2
Which observation best illustrates cellular homeostasis?
- Organic molecules are present.
- Inorganic molecules are present.
- All intracellular concentrations change without regulation.
- The cell regulates internal conditions within a range despite external changes.
- The cell contains no water.
Question 3
Which of the following is not found in single celled organisms?
- atoms
- cells
- tissues
- Neither A nor B is found in single celled organisms.
- Neither A, nor B, nor C is found in single celled organisms.
Question 4
Evidence that all living cells have a common origin is provided by:
- the cell theory, which states that the cell is the basic unit of life.
- the fact that all new cells come from previously existing cells.
- the fact that cells are the building blocks of the most complex plants.
- basic similarities in cell structure and chemistry.
- the fact that cells are the smallest units that can carry out all life activities.
Question 5
Which molecule stores the hereditary sequence information used to direct protein synthesis?
- proteins
- mitochondria
- cell membranes
- DNA
- ribosomes
Question 6
The function of the plasma membrane is to:
- serve as a highly selective barrier.
- completely isolate the cell from the external environment.
- equalize the chemical composition inside and outside the cell.
- allow cells to accumulate materials and energy.
- Both A and D.
Question 7
It is advantageous for cells to be small because:
- a small cell size prevents a cell from weighing too much.
- a small cell size occupies less space in nature where space is limited.
- a small cell has a small volume relative to surface area, thereby increasing efficient transport.
- a small cell has a small surface area relative to volume, thereby facilitating ion balance.
- a small cell is better able to conserve energy than a larger cell.

Question 8
Which of the following statements about Figure 04-01 is true?
- Figure B has a greater surface area than Figure A.
- Figure B has a greater volume than Figure A.
- Figure B has a smaller volume than Figure A.
- Figure B has a greater surface area to volume ratio than Figure A.
- Figure B has a smaller surface area to volume ratio than Figure A.
Question 9
For the 100 µm cube B in Figure 04-01, what is its surface-area-to-volume ratio in µm⁻¹?
- 0.01.
- 0.06.
- 100.
- 1,000.
- This cannot be determined from the information provided.
Question 10
One strategy that allows larger cells to have an effective surface area to volume ratio is:
- having a completely spherical shape.
- being short and fat.
- having thin, finger-like projections.
- having a thinner plasma membrane.
- locomotion.
Question 11
Which statement does not describe cellular homeostasis?
- A cell regulates its internal pH within a suitable range.
- A cell regulates its internal ion concentrations.
- A cell adjusts water balance as conditions change.
- A cell uses feedback mechanisms to regulate internal conditions.
- A cell allows all internal conditions to vary without regulation.
Question 12
Which of the following descriptions or structures does not match the cell type?
- Sperm cells have flagella.
- Nerve cells have long, thin extensions.
- All epithelial cells have exactly the same shape.
- White blood cells can change shape.
- All of the above are correct.
Question 13
Which scientist first viewed living cells?
- Robert Hooke
- Matthias Schleiden
- Theodor Schwann
- Anton van Leeuwenhoek
- August Weismann
Question 14
The ratio of the size of the image seen with the microscope to the actual size of the object is:
- magnification.
- resolution.
- resolving power.
- centrifugation.
- None of the above.
Question 15
Electron microscopes have a much higher resolution than either the human eye or any light microscope because:
- of their higher magnification.
- the lenses used are of much higher quality.
- the electron beam has a much shorter effective wavelength than visible light.
- the images are viewed on screens, rather than directly using an eyepiece or ocular lens.
- All of the above.
Question 16
The advantage of studying cells using a phase contrast microscope is that:
- the magnification is greater.
- the resolving power is greater.
- it is faster.
- it permits us to view internal structures of live cells.
- it uses a beam of electrons to allow us to see the organelles enclosed by the plasma membrane.

Question 17
The accompanying figure is the product of a:
- phase-contrast light microscope.
- Nomarski differential interference microscope.
- transmission electron microscope.
- scanning electron microscope.
- confocal fluorescence microscope.
Question 18
Which feature is especially characteristic of a conventional scanning electron microscope rather than a conventional transmission electron microscope?
- It routinely images living specimens.
- It uses visible light instead of electrons.
- It images internal structures by transmitting electrons through thin sections.
- It requires no specimen preparation.
- It produces detailed surface images with a three-dimensional appearance.
Question 19
Differential centrifugation is a process that:
- separates different components of the cell that function differently.
- separates components of the cell that have a different chemical makeup.
- analyzes the chemical components of the cell.
- separates cell components by differences in sedimentation rate, influenced by size and density.
- allows researchers to view the contents of the cells.
Cell structures and organelles
Question 20
Which structure is found in eukaryotic cells but is absent from prokaryotic cells?
- cell wall
- flagellum
- ribosomes
- Golgi apparatus
- DNA
Question 21
Membrane-bounded organelles facilitate faster chemical reactions because:
- reactants are within close proximity to each other.
- membranes lower the activation energy of biochemical reactions.
- membrane-bounded organelles act as catalysts for biochemical reactions.
- reactants move faster within membrane-bounded organelles.
- reactants are less likely to encounter each other within membrane-bounded organelles.
Question 22
A eukaryotic cell:
- is usually smaller than a prokaryotic cell.
- has its DNA concentrated in one area of the cell without a nuclear membrane.
- typically has a cell wall, in addition to a plasma membrane.
- is a bacteria-like organism.
- has a variety of membranous organelles.
Question 23
Which task is performed by genetic sequence information rather than being a direct function of cellular membranes?
- facilitating the formation of energy-yielding gradients.
- acting as barriers to ions.
- acting as important "work benches" within cells.
- specifying the amino-acid sequence of a protein.
- maintaining the identity of different cellular compartments.
Question 24
Which structure is generally absent from ordinary nonphotosynthetic cells in underground plant roots?
- mitochondria
- chloroplasts
- endoplasmic reticulum
- nucleus
- All of the above would be found in cells of a plant's root.
Question 25
Which organelle-function pairing is incorrect?
- Mitochondria: ATP production associated with cellular respiration.
- Ribosomes: assembly of polypeptides.
- Smooth endoplasmic reticulum: assembly of polypeptides from amino acids.
- Chloroplasts: photosynthesis in plant leaf cells.
- Golgi apparatus: modification and sorting of proteins.
Question 26
Which organelle is not part of the endomembrane system?
- smooth endoplasmic reticulum
- lysosome
- transport vesicle
- peroxisome
- Golgi apparatus
Question 27
DNA is associated with proteins, forming a complex known as:
- chromosomes.
- nucleoli.
- nucleus.
- genes.
- chromatin.
Question 28
In the classic experiments by Bracht and Hammerling, the nucleus of Acetabularia was removed, the cap was cut off, a nucleus of a different species was inserted, and the cap was allowed to regenerate. The new cap was then removed. After the second regeneration, the cap was observed, and the following conclusion was made:
- The shape of the cap was controlled by the nucleus, thus, the nucleus was the control center of the cell.
- The shape of the cap was under the control of the stalk, which produced a control substance.
- The shape of the cap was independent of both the stalk and the holdfast.
- The "cren" caps were defective due to some mutation in the cap. Thus, "cren" caps are independent of control from both the base and the holdfast.
- At the time no conclusion could be made because in the early 20th century, biologists did not know about the composition of DNA.
Question 29
Chromosomal regions within the nucleolus include genes transcribed to produce which major component of ribosomes?
- cellulose
- ribosomal RNA (rRNA)
- phospholipids
- glycogen
- cholesterol
Question 30
If a toxin, such as a bacterial toxin, destroys ribosomes, what cellular activity will be affected first?
- protein synthesis
- DNA synthesis
- movement
- energy storage
- active transport
Question 31
Proteins made on ribosomes may be further modified within the:
- lysosomes.
- nucleus.
- mitochondria.
- Golgi complex.
- peroxisomes.
Question 32
The smooth endoplasmic reticulum:
- is absent in most plant cells.
- synthesizes proteins.
- provides structural support.
- synthesizes lipids.
- is required for ribosome synthesis.

Question 33
The cellular structure indicated by the arrow in Figure 04-02 is responsible for:
- lipid and fatty acid metabolism.
- protein synthesis.
- digestion of unused organelles.
- replication.
- None of the above.
Question 34
Which of the following statements about the structure surrounded by the box in Figure 04-02 is true?
- This structure is only found in plant cells.
- This structure is characteristic of both prokaryotic and eukaryotic cells.
- This structure plays a central role in the process of transcription.
- This structure typically represents a significant portion of the overall cell volume.
- This structure represents the main storage area for the cell.
Question 35
Which of the following pairs is correctly matched?
- chloroplast – storage of enzymes
- lysosome – powerhouse of the cell
- nucleolus – site of ribosomal subunit synthesis
- plastids – structural support of the cell
- Golgi complex – production of energy
Question 36
Which of the following organelles plays an important role in apoptosis, or programmed cell death?
- ribosomes
- mitochondria
- chloroplasts
- vacuoles
- peroxisomes
Question 37
One function of peroxisomes involves the process of:
- cell death.
- water storage.
- protein synthesis.
- DNA replication.
- detoxification.
Question 38
During an infection, white blood cells travel to the infected site and phagocytize the pathogens. After phagocytosis, primary lysosomes fuse with the phagocytic vesicle to form a larger vesicle called a secondary lysosome. The reason for this is:
- to introduce antibodies to the phagocytic vesicles.
- to wrap the pathogen in additional membrane, rendering them harmless.
- to coat the bacteria in lipids derived from the Golgi complex, which cover and smother them.
- to mix the pathogens with strong hydrolytic enzymes and destroy them.
- to prepare the bacteria for export from the body.
Question 39
All of the following functions are performed by plant vacuoles except:
- maintaining hydrostatic (turgor) pressure.
- waste storage and recycling.
- storage of proteins.
- breakdown of unneeded cellular materials.
- storage of nucleic acids.
Question 40
The theory that chloroplasts and mitochondria had their evolutionary beginnings in eukaryotic cells as endosymbionts is supported by all of the following except:
- chloroplasts and mitochondria are completely autonomous within eukaryotic cells.
- chloroplasts and mitochondria have DNA.
- chloroplasts and mitochondria have small ribosomes for protein synthesis.
- chloroplasts and mitochondria are approximately the same size as prokaryotic cells.
- chloroplasts and mitochondria contain genetic material with features related to bacterial genetic material.
Question 41
A cellular structure found in plant but not animal cells is the:
- chloroplast.
- ribosome.
- endoplasmic reticulum.
- microtubule.
- microfilament.

Question 42
Refer to Figure 04-03. The formation of ATP occurs in the portion of the chloroplast labeled:
- structure A.
- structure B.
- structure C.
- structure D.
- structure E.
Question 43
The formation of carbohydrates from carbon dioxide and water occurs in the portion of the chloroplast in Figure 04-03 labeled:
- structure A.
- structure B.
- structure C.
- structure D.
- structure E.
Question 44
Which of the following is a key component of the cytoskeleton?
- membranes
- microtubules
- DNA
- ribosomes
- None of the above.
Question 45
The force necessary to cause microtubules of cilia and flagella to slide alongside one another is provided through the action of _________ proteins, which derive the energy to perform their work directly from ______ molecules.
- kinesin; ADP
- kinesin; glucose
- tubulin; ATP
- dynein; ATP
- dynein; ADP

Question 46
The structures in the micrograph could be:
- chloroplasts.
- cilia.
- RER.
- flagella.
- B and D

Question 47
The organelle featured in Figure 04-04:
- is present in a few prokaryotes.
- is the major site of protein synthesis in the cell.
- plays a vital role in packaging materials to be secreted.
- plays a central role in energy metabolism.
- is located in the nucleus.
Question 48
The structures indicated by the arrows in Figure 04-04 are:
- thylakoid lamellae.
- grana.
- cristae.
- matrices.
- plastids.
Question 49
The main process that occurs at the site of the structures marked by arrows in Figure 04-04 is:
- protein synthesis.
- photosynthesis.
- conversion of food molecules to ATP.
- processing and packaging of proteins.
- transcription.
Question 50
A single cell in a smoker's lung has become cancerous. It doubles its DNA and divides much faster than a normal lung cell. The most likely change that would have caused this condition took place in the:
- nucleus.
- nucleolus.
- microtubule.
- mitochondria.
- lysosome.
Question 51
Cells have internal structures called organelles. Which is not a function of organelles?
- Store genetic information.
- Convert energy to more usable forms.
- Synthesize polymers.
- Manufacture membranes.
- All of the above are organelle functions.
Question 52
Which of the following is not a cell covering or part of a cell covering?
- glycocalyx
- extracellular matrix
- cristae
- cell wall
- integrins
Question 53
The principle cell adhesion molecules in vertebrates and in many invertebrates are cadherins. These are important in:
- preventing the invasiveness of some malignant tumors.
- calcium-dependent adhesion between cells that form multicellular sheets.
- embryonic development.
- cell adhesion in vertebrates and in many invertebrates.
- All of the above.
Membranes and transport proteins
Question 54
All of the following are functions of the cell membrane except:
- transmitting signals.
- participating in energy transfer.
- being freely permeable.
- regulating the passage of materials.
- participating in chemical reactions.
Question 55
Which of the following structures is composed of two layers of phospholipids associated with proteins integrated within or attached to these layers?
- cell wall
- plasma membrane
- microfilaments
- flagellum
- ribosomes
Question 56
Phospholipids can form bilayer structures because of their:
- rectangular shapes.
- amphipathic nature.
- ability to dissolve well in water.
- inability to associate with other phospholipids.
- lack of fatty acids.
Question 57
Phospholipids can form bilayers because the molecules:
- have two distinct regions, one strongly hydrophobic and the other strongly hydrophilic.
- are amphipathic molecules.
- have cylindrical shapes that allow them to associate with water most easily as a bilayer structure.
- Both A and B.
- A, B, and C.
Question 58
A key discovery that weakened the Davson-Danielli "sandwich" model of cell membranes was that:
- membrane proteins form a solid sheet on either side of the phospholipid bilayer.
- membrane proteins form a solid sheet separating the phospholipid layer.
- the phospholipids do not associate with each other in the hydrophobic region of membranes.
- membrane proteins were not uniform and did not form flattened sheets.
- membrane proteins occurred in regular organized patterns on the surface of membranes.
Question 59
Proposed the fluid mosaic model of cell membrane structure in 1972:
- S. Jonathan Singer.
- Garth Nicolson.
- Hugh Davson.
- Both A and B.
- A, B, and C.
Question 60
Which is a typical lipid component of an animal cell plasma membrane?
- DNA
- glucose
- cholesterol
- water
- All of the above.
Question 61
Cholesterol within membranes functions as a(an) ____________ through its interactions with both hydrophobic and hydrophilic parts of phospholipids.
- water blocker
- pH buffer
- energy source
- temperature controller
- fluidity buffer
Question 62
In a lipid bilayer, ___________ fatty acid tails face each other within the bilayer and form a region that excludes water.
- hypertonic
- hyperosmotic
- hypotonic
- hydrophilic
- hydrophobic
Question 63
Which of the following functions best explains the reason for the asymmetrically oriented structure of the proteins in the cell membrane?
- These proteins are manufactured by free ribosomes.
- Each type of protein has its own function.
- These proteins pass through the ER membrane into the ER lumen.
- Enzymes are needed to modify the carbohydrate chains on these proteins.
- These proteins are initially formed by ribosomes on the rough ER.
Question 64
Which of the following is not a function associated with membrane proteins?
- Recognition of surface antigens of bacterial cells.
- Forming junctions between adjacent cells.
- Identify the cell as belonging to a particular individual.
- Serve as anchoring points for networks of cytoskeletal elements.
- All of the above are functions associated with membrane proteins.
Question 65
Which statement best describes the function of aquaporins?
- They pump water against its gradient using ATP directly.
- They form channels that facilitate passive water movement across a membrane.
- They synthesize phospholipids.
- They digest proteins inside lysosomes.
- They carry DNA into the nucleus.
Question 66
Catalysts are reusable. Enzymes are protein catalysts, and are reusable. Select the protein(s) below that is (are) not used up by the process carried out:
- Sodium-potassium pump carrier proteins
- Aquaporins
- Proteins involved in facilitated diffusion
- Both A and B.
- A, B, and C.
Question 67
Integral proteins:
- are weakly bound to the surface of the membrane.
- are strongly bound to the cytosolic surface of the membrane.
- have no hydrophobic portions.
- are completely embedded within the lipid bilayer.
- are amphipathic.
Question 68
What is meant by the term "fluid mosaic model"?
- It is the diffusion of lipid-soluble substances through the lipid bilayer.
- It is the movement of lipids and integral proteins within the lipid bilayer.
- It is the solubility of water in the membrane.
- It is the method of substance transport across the membrane.
- It is the movement of surface proteins through the membrane.
Question 69
A transmembrane protein differs from other membrane proteins because it:
- is covalently linked to the outer surface of the plasma membrane.
- is a glycoprotein with carbohydrates attached.
- is attached to the inside of the membrane by an ionic bond .
- completely extends through the membrane.
- is completely embedded within the membrane.
Question 70
Peripheral proteins are linked to either surface of the plasma membrane by:
- covalent disulfide bonds.
- associating with fatty acids through hydrophobic interactions.
- embedding in one side of the membrane and, thus, not extending through to the other side.
- associating with glycoproteins on the inner membrane surface.
- bonding to integral proteins through weak linkages.
Question 71
Which of the following statements explaining the differences in number and types of peripheral proteins found on the inner and outer surfaces of cell membranes is correct?
- The functions of the membrane differ on the inside and outside of the cell.
- Not all proteins can pass through the membrane and, thus, more accumulate on the inside.
- Proteins on the outside of the membrane are synthesized at a slower rate than proteins on the inside of the membrane.
- Proteins on the outside of membrane are made extracellularly and are unable to penetrate the phospholipid bilayer and enter the cell.
- The external peripheral proteins are weakly attached to the membrane and are readily washed away.
Question 72
Proteins that are destined to become associated with the inner surface of the plasma membrane are:
- manufactured in the same way as protein hormones.
- manufactured in the same way as proteins destined to become external peripheral proteins.
- made on free ribosomes in the cytoplasm.
- made on ribosomes located on the rough endoplasmic reticulum.
- transported to the plasma membrane within a secretory vesicle.
Diffusion, osmosis, and transport
Question 73
Biological membranes are normally permeable to:
- large, hydrophilic molecules.
- small, hydrophilic molecules.
- large, hydrophobic molecules.
- small, hydrophobic molecules.
- None of the above.
Question 74
A bottle of perfume is opened on the opposite side of the room and within minutes you begin to smell the perfume. This phenomenon is a classic example of:
- dialysis.
- osmosis.
- active transport.
- facilitated diffusion.
- diffusion.
Question 75
Which of the following molecules is least likely to cross a cellular membrane by simple diffusion?
- carbon dioxide
- nitrogen
- oxygen
- potassium ion
- water
Question 76
The passive movement of a substance along its concentration gradient is termed:
- active transport.
- dialysis.
- diffusion.
- exocytosis.
- osmosis.
Question 77
Which type of molecule generally passes most readily through the hydrophobic core of a phospholipid bilayer without a transport protein?
- small polar molecules
- small nonpolar molecules
- large polar molecules
- large nonpolar molecules
- water
Question 78
The difference between dialysis and osmosis is that:
- in osmosis, the solute moves through a selectively permeable membrane.
- in dialysis, the solvent moves through a selectively permeable membrane.
- in osmosis, the solute moves from a region of high concentration to a region of low concentration.
- in dialysis, the solute moves from a region of high concentration to a region of low concentration.
- in dialysis, the solvent moves from a region of high concentration to a region of low concentration through a selectively permeable membrane.
Question 79
If the concentration of solutes in a cell is less than the concentration of solutes in the surrounding fluid, then the extracellular fluid is said to be:
- hypertonic.
- hypotonic.
- isotonic.
- stable.
- amphipathic.
Question 80
The higher the concentration of solute in a solution, the _________ the effective water concentration and the ________ the osmotic pressure.
- lower; lower
- lower; higher
- higher; higher
- higher; lower
- Answer cannot be determined from the information provided.

Question 81
Which of the following statements about the red blood cells in Figure 05-01 Sample B is true?
- These red blood cells have been placed in an isotonic solution.
- These red blood cells have swollen in response to a hypertonic external solution.
- These red blood cells have swollen in response to a hypotonic external solution.
- These red blood cells have shrunken in response to a hypertonic external solution.
- These red blood cells have shrunken in response to a hypotonic external solution.
Question 82
Which of the following statements about the red blood cells in Figure 05-01 Sample A is true?
- There has been no net water movement.
- There has been a net flow of water out of the cell.
- There has been a net flow of water into the cell.
- Pinocytosis has occurred.
- Plasmolysis has occurred.
Question 83
A patient who has had a severe hemorrhage accidentally receives a large transfusion of distilled water directly into a major blood vessel. You would expect this mistake to:
- have no unfavorable effect as long as the water is free of bacteria.
- have serious, perhaps fatal consequences because there would be too much fluid to pump.
- have serious, perhaps fatal consequences because the red blood cells could shrink.
- have serious, perhaps fatal consequences because the red blood cells could swell and burst.
- have no serious effect because the kidney could quickly eliminate excess water.
Question 84
A plant cell placed in a hypertonic solution will:
- remain unchanged.
- undergo lysis.
- undergo plasmolysis.
- swell slightly.
- become crenated.
Question 85
Penicillin is toxic to certain dividing bacterial cells because it prevents cell wall formation, causing the cells to burst. This indicates that the bacteria live in:
- a hypotonic medium.
- a hypertonic medium.
- an isotonic medium.
- a medium with higher osmotic pressure than the cell.
- Both B and D.
Question 86
A wilted flower placed in a vase of water for several hours became stiff and stood erect. When it was placed in a salt solution, it wilted. From this information we can say that the cells of the flower are:
- hypotonic to both fresh water and the salt solution.
- hypertonic to both the fresh water and the salt solution.
- hypertonic to fresh water but hypotonic to the salt solution.
- hypotonic to fresh water but hypertonic to the salt solution.
- isotonic to fresh water but hypotonic to the salt solution.
Question 87
Which of the following membrane activities does not require the expenditure of energy by the cell?
- active transport
- osmosis
- endocytosis
- exocytosis
- synthesis of more membrane
Question 88
Facilitated diffusion:
- requires a transmembrane protein.
- requires ATP.
- can move molecules against a concentration gradient.
- is typically used to transport small nonpolar molecules.
- All of the above.
Question 89
A bacterium accumulates sodium ions uphill against their electrochemical gradient. Which mechanism can drive this accumulation?
- active transport.
- endocytosis.
- diffusion.
- facilitated diffusion.
- osmosis.
Question 90
The energy-requiring movement of materials against a concentration gradient is termed:
- active transport.
- dialysis.
- facilitated diffusion.
- osmosis.
- plasmolysis.
Question 91
Which immediate conversion helps maintain a low concentration of free glucose inside a cell after glucose enters?
- conversion of glucose directly into protein
- excretion of glucose into the surrounding fluid
- phosphorylation of glucose to glucose-6-phosphate
- active pumping of all glucose out of the cell
- engulfment of glucose by pinocytosis
Question 92
Which of the following statements about the sodium-potassium pump is true?
- It transports hydrogen ions out of the cell.
- It transports 3 sodium ions out of the cell in exchange for 2 potassium ions.
- It transports 2 sodium ions out of the cell in exchange for 2 potassium ions.
- It transports 2 sodium ions out of the cell in exchange for 3 potassium ions.
- It transports water directly out of the cell.
Question 93
A person has a genetic disease that prevents the phospholipids in the plasma membrane of the white blood cells from freely fusing with the other membranes within the cell. How would this disease affect phagocytosis?
- Lysosomes would not be formed.
- Facilitated diffusion would not occur.
- Lysosomes would be formed lacking hydrolytic enzymes.
- The phagocytic vacuole would not fuse with the lysosome.
- Endocytosis would not occur.
Question 94
Which of the following are forms of carrier-mediated transport?
- Facilitated diffusion.
- Carrier-mediated active transport.
- Osmosis.
- Both A and B.
- A, B, and C.
Question 95
Which statement describes facilitated diffusion itself?
- A substance moves downhill through a channel or carrier without direct ATP use by that transport step.
- A substance is pumped uphill against its electrochemical gradient.
- ATP must bind and be hydrolyzed in every transport cycle.
- Transport requires a membrane vesicle.
- Only small nonpolar molecules can be transported.
Vesicles, junctions, and cell signaling
Question 96
Pinocytosis:
- is engulfment of large particles by the cell.
- occurs in protozoans and algae but not in more complex organisms.
- involves the specific binding of molecules to receptors on the cell surface.
- is the nonspecific uptake of fluids by an invagination of the cell membrane.
- is movement of molecules against the concentration gradient through a permeable membrane.
Question 97
Receptor-mediated endocytosis:
- is a passive process.
- involves only membrane transport proteins.
- brings about the selective uptake of materials by enclosing them in membranous vesicles.
- does not require energy.
- is most likely to be found in cells that release large amounts of hormones.
Question 98
A human white blood cell engulfs a bacterial cell by:
- carrier-mediated facilitated diffusion.
- exocytosis.
- phagocytosis.
- pinocytosis.
- the sodium-potassium pump.
Question 99
Which event occurs before a coated vesicle forms during receptor-mediated endocytosis?
- The incoming cargo is digested in a lysosome.
- A ligand binds to a receptor at the cell surface.
- The vesicle releases its cargo outside the cell by exocytosis.
- The newly internalized receptor is recycled to the surface.
- The ligand separates from its receptor inside an endosome.
Question 100
In cells that are constantly involved in secretion, an equivalent amount of membrane must be returned to the interior of the cell for each vesicle that fuses with the plasma membrane; if this does not occur, then what would happen?
- The ratio of cell surface would decrease, compared to cell volume.
- The cell surface would shrivel.
- The surface area would remain constant.
- The number of membrane receptor proteins would decrease.
- The cell surface will keep expanding.

Question 101
The process illustrated in Figure 05-02 is called:
- facilitated diffusion.
- pinocytosis.
- cotransport.
- lysis.
- exocytosis.
Question 102
The process illustrated in Figure 05-02 would most likely be used to transport:
- glucose.
- hormones.
- potassium ions.
- carbon dioxide.
- bacteria.
Question 103
One difference between tight junctions and desmosomes is that tight junctions:
- form continuous seals that restrict movement between neighboring epithelial cells.
- occur only in plants.
- involve connective microfilaments that traverse the space between adjacent cells.
- are anchored by microfilaments on the insides of the cell membranes of adjacent cells.
- contain a 24 nm space between two adjacent membranes.
Question 104
Plasmodesmata of plant cells are functionally equivalent to ____________ of animal cells.
- gap junctions
- desmosomes
- tight junctions
- cell surface receptors
- microvilli

Question 105
The structures in this figure:
- provide anchorage points between adjacent cells.
- allow the transport of small molecules and ions between adjacent cells.
- allow passage of materials through intercellular spaces.
- prevent the passage of materials through intercellular spaces.
- can only be found in plants.
Question 106
Which of the following is not part of the process of cell signaling?
- Synthesis and release of signaling molecules.
- Facilitated transport.
- Transport to target cells.
- Response by the cell.
- Termination of signaling.
Question 107
The process in which cells convert and amplify an extracellular signal into an intracellular signal:
- Synthesis and release of signaling molecules.
- Transport to target cells.
- Signal transduction.
- Response by the cell.
- Termination of signaling.
Question 108
In a signaling pathway, the second messenger is often:
- GTP.
- GDP.
- cyclic AMP.
- cyclic ADP.
- ATP.
Teacher notes and sources
This is a classroom question bank, not a timed online test. No complete answer key is supplied. Use a separate answer sheet and discuss the evidence for each selected response. Small, inherited image labels may be easier to read at full size. Retain existing figure credits and check permissions before redistributing the figures.
For the membrane-protein terminology in question 69, see the existing ionic bond resource.
AP Introduction, Chemistry, and Water
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Scientific Method Web Quest: Compare Questions, Methods, and Evidence
Biology Foundations and Lab Skills Teaching Resources · High school biology; AP extensions where noted.
This guided reading task asks students to compare descriptions of scientific inquiry and then design a testable investigation on paper. The aim is to explain how evidence is used, rather than copy a list of steps from a website.
Learning goals and preparation
- Distinguish questions, explanations, predictions, and evidence.
- Compare a simplified classroom sequence with inquiry in practice.
- Credit a source and explain an idea in original words.
Prerequisite: scientific method notes. Materials: paper or a document editor and access to the two readings below. The teacher should open the readings before assigning them; a printed excerpt selected under the source’s terms or a teacher explanation can replace web access.
Reading stations
- OpenStax: The Process of Science. Find how the reading distinguishes a hypothesis from a prediction and how evidence is used to examine an explanation.
- College Board: AP Biology Lab Manual Resource Center. Read the overview of inquiry-based investigations. Identify examples of decisions students can make about methods, measurements, or analysis. This is a source about teaching inquiry, not a required procedure for this activity.
Student response sheet
Record the title, organization, URL, and date accessed for each reading. In your own words, answer:
- What makes a question investigable with scientific evidence?
- How does a prediction differ from a proposed explanation?
- Why might a researcher return to an earlier question or revise a method?
- What useful role does a classroom sequence play? What does it leave out?
- How could observations contribute to an investigation without a manipulated treatment?
Apply what you learned
Plan a paper investigation of how water availability might affect seed germination. Define “germinated,” the measurement period, treatment levels, independent experimental units, conditions kept comparable, and an appropriate comparison. Explain what pattern would support your prediction and what alternative explanation would still need attention. No seeds, chemicals, or organisms are handled during this web quest.
Teacher feedback
A useful plan names observable outcomes and avoids treating “better growth” as a measurement. If seeds share a container, students should consider whether the container rather than each seed is the independently treated unit. A good response credits sources, distinguishes the two readings’ purposes, and acknowledges uncertainty. Do not require an “if–then” sentence as the only acceptable form of a scientific hypothesis.
Assessment: check accurate concepts, specific design choices, reasons for those choices, and source credit. For AP extension, ask students to identify a confound and propose a better sampling or treatment-assignment strategy.
